Click&ScoreTM – a single click on a comet initiates & completes the entire measurement cycle. Measurement performed & results returned instantly. Ability to score ‘blind’ if desired. Comets can be scored live or from saved images.
No constrains on study scope or layout. Any number of cells per slide. Configurable message appears when set number of comets have been scored.
With Click&Score, users can score a typical slide in two minutes. Individual cells are scored instantly.
Help & Tutorials
In-depth help system includes tutorials and comprehensive guides on system setup and configuration.
Unlimited number of system configurations can be created for different study requirements. Configurations include setup information on how the system operates in a specific situation.
Unlimited number of calibrations can be saved for different microscope objectives.
Each system configuration can be configured with any number of headings for study ID, slide ID, dose etc. Configurable as revert to blank or revert to previous entry.
Electronic Records & Signatures
Compatible with the System Access Manager for compliance with FDA 21 CFR Part 11 Final Rule on Electronic Records & Electronic Signature.
Encoded audit trail files automatically record all system activity including settings, measurement data and edits. Audit trail data can also be sent directly to an Oracle database.
Supervisor & User levels.
User Access Rights
Supervisors may lock any of the menus, or selected options within them, to deny Users access to particular functions.
Comprehensively tested and validated in accordance with our Quality Management System which is approved to ISO 9001:2008 incorporating ISO 90003. Validation and project documentation supplied with system.
Full pseudocolour overlay and onscreen gamma correction to help users visualise cells.
Data Processing & Transfer
Powerful new macros allow users to compare data across dose ranges. Macros include statistics, log transforms & frequency distribution graphs. Configurable data transfer to Oracle database.
All core Comet assay measurement parameters: Tail % intensity, Head % intensity, Olive tail moment, Tail length, Head length, Tail moment, Total area, Mean grey level, Width, Total intensity. Also allows a tally of hedgehog cells to be created.
Interactive editing of head, middle of head and tail positions for badly damaged cells.
High resolution monochrome FireWire CCD camera provides live video at 25 frames per second.
Fully automatic adaptive background correction that requires no configuration of settings.
Invert video option for scoring silver stained slides.
Freeze image, Go live, Save to file, Load from file. Range of image loading functions including compatibility with TWAIN devices. Audit image save & retrieve saves images with measurement frame position, allowing measurements to be reproduced at a later date.
Microsoft Windows XP, 7 or 8. Microsoft Office 2002 or later. Oracle 10g, 11g or 12c if you intend to connect to a database. One free FireWire port, or one free PCIe slot for FireWire expansion board.