Comet Assay
Perceptive Instruments have supplied application software for the Comet assay since 1992. We are proud to have equipped and gained invaluable advice and feedback from leading exponents of the assay for over a decade. We are the only supplier of Comet assay software that has attained ISO 9001:2000 approval for its Quality Management system from a UKAS accredited certification body. Live interactive scoring software for the comet assayOur Comet assay systems have always been regarded as the fastest and easiest to use. They are used in universities, research institutes, hospitals, pharmaceutical companies and contract research organisations throughout the world. Our latest system, Comet Assay IV, uses a live video picture direct from the microscope so that comet slides can be analysed in real time. All recommended measurements are automatically computed, including % Tail DNA, Tail Length and Olive Tail Moment. Powerful Excel macros are available for data processing, statistical analysis and charting. Data can also be sent directly to Oracle or Microsoft Access databases. Comet Assay IV is fully validated and is compliant with Good Laboratory Practice (GLP) and FDA 21 CFR Part 11. Encoded audit trail files automatically record all system activity including settings, measurement data and edits. Comet Assay IV also incorporates hierarchical access and system passwords. Comet Assay IV overview | Linus Pauling Institute - Comet assay overview |
The
Comet assay, or Single-Cell Gel Electrophoresis Technique, was developed
in the late 1980's by Swedish researchers Ostling & Johansson as a
fast, effective way of measuring DNA strand breaks in individual cells.
The Comet assay is used for a wide range of applications, including DNA
damage and repair studies, genetic toxicology testing, biomonitoring and
nutritional research.