Perceptive Instruments Ltd., founded in 1990, develops, manufactures and supplies image analysis and data processing solutions for many areas of scientific research and industry.
Ames Study Manager is a software suite for conducting and reporting regulatory Ames studies in accordance with OECD 471 and the principles of GLP. Linking directly with Sorcerer for plate counting, Ames Study Manager is used to save study designs, capture count information and produce final study reports. With a global install base and advanced features such as managing historical control data and archiving studies, it is firmly established as the de facto data collection and reporting system for the Ames test.
As well as automatically generating data tables and study reports on the fly, custom reports can be created for plate preparation, auditing or anything else you need. We can even tailor these reports to match your own corporate style.
Ames Study Manager is able to handle any experimental design and imposes no constraints for numbers of experiments, strains, test substances, or positive & negative controls etc. Each study created with the Ames Study Manager can have any number of individual experiments, each unique in design. Designs can be saved as templates for future studies.
Both the Ames Study Manager and Sorcerer Colony Counter have been designed in line with the specifications of the regulatory guidelines, including 21 CFR, ICH S2(R1) and OECD 471.
The Ames test, named after its developer Dr Bruce Ames, is the most widely used regulatory test for genotoxicity. Testing for genotoxicity is mandatory for pharmaceuticals, medical devices, food additives, agrochemicals and industrial chemicals (see OECD Guideline 471).
The Ames test uses several strains of the bacterium Salmonella typhimurium. These strains carry mutations in the histidine synthesis gene and require histidine for normal growth; they aree known as auxotrophic mutants. When a mutation in the histidine genes occur, the bacteria can revert back to the non-auxotrophic state; this allows the cells to grow on a histidine-free medium. Counting these colonies generates Ames test data.
Perceptive Instruments have supplied colony sizing and data processing systems for the Ames test for over a decade.
Find out more about Sorcerer Colony Counter.
Find out more about Ames Study Manager.
"Innovative software solutions for genetic toxicology assays"
Perceptive Instruments help you integrate data acquisition, auditing and reporting for your genetic toxicology assays. With over 20 years' experience, we have always delivered highly effective solutions along with excellent customer service. We have a reputation for quality and operate a quality management system to IS0 9001:2008. Over 90% of our sales are made internationally; we have extensive experience in selling, shipping, installing and supporting our products to a global market.
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